About 28 results found for searched term "Alkaline phosphatase" (0.18 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M11157 | Alkaline phosphatase | Metabolite/Endogenous Metabolite |
| Alkaline phosphatase is a membrane-binding glycoprotein that catalyzes the hydrolysis of monos phosphate esters at alkaline pH. Alkaline phosphatase can be used for molecular biology and enzyme-free analysis. | ||
| M2865 | Sodium Monofluorophosphate | Pyruvate Kinase |
| Monofluorophosphate is a competitive inhibitor of pyruvate kinase and alkaline phosphatase with Ki of 3.4 mM and 69 μM, respectively, which also irreversibly inhibits phosphorylase phosphatase with Ki of 0.5 mM. | ||
| M21540 | L-Ascorbic Acid 2-phosphate (magnesium salt hydrate) | Phosphatase |
| L-Ascorbic Acid 2-phosphate (magnesium salt hydrate) is a long-term vitamin C derivative that can stimulate the expression and formation of collagen. L-Ascorbic Acid 2-phosphate (magnesium salt hydrate) can be used as a medium to supplement osteogenic differentiation of human adipose stem cells (hASCs). Increased alkaline phosphatase (ALP) activity and runx2A expression in hASC during osteoblast differentiation. | ||
| M5161 | Sodium orthovanadate | ATPase |
| Sodium vanadate | ||
| Sodium orthovanadate is an alkaline phosphatase and (Na,K)-ATPase inhibitor with IC50 of 10 μM. | ||
| M5348 | (-)-Tetramisole | Others |
| (-)-Tetramisole hydrochloride | ||
| (-)-Tetramisole is an inhibitor of alkaline phosphatase, used as an anthelmintic. | ||
| M6300 | (-)-p-Bromotetramisole Oxalate | Phosphatase |
| L-p-Bromotetramisole Oxalate | ||
| (-)-p-Bromotetramisole Oxalate is a potent and non-specific alkaline phosphatase inhibitor. | ||
| M9037 | AMPPD | Fluorescent Dye |
| Lumigen PPD | ||
| AMPPD is a new biochemistry ultrasensitive alkaline phosphatase substrate. | ||
| M9399 | PNPP disodium | Fluorescent Dye |
| PNPP (Para-nitrophenyl phosphate) disodium is a non-proteinaceous chromogenic substrate for alkaline and acid phosphatases used in ELISA and conventional spectrophotometric assays. | ||
| M9759 | Recombinant Human BMP-4 (HEK293, C-Fc) | Recombinant Proteins |
| Bone Morphogenetic Protein-4; BMP-2B | ||
| BMP-4 is involved in the development and maintenance of bone and cartilage. Bone morphogenetic proteins (BMPs) constitute a subfamily within the TGF-β superfamily of structurally related signaling proteins. Measured by its ability to induce ATDC-5 cells to produce alkaline phosphatase, the ED50 is ≤50 ng/mL. | ||
| M9793 | Nitrotetrazolium Blue chloride | Fluorescent Dye |
| NBT | ||
| Nitrotetrazolium Blue chloride (NBT) is a substrate for dehydrogenases, used with the alkaline phosphatase substrate 5-Bromo-4-Chloro-3-Indolyl Phosphate (BCIP) in western blotting and immunohistological staining procedures. | ||
| M11036 | L-Ascorbic acid 2-phosphate | Others |
| 2-Phospho-L-ascorbic acid | ||
| L-ascorbic acid 2-phosphate is a long-acting vitamin C derivative that stimulates collagen expression and formation. L-ascorbic acid 2-phosphate increases alkaline phosphatase (ALP) activity and runx2A expression in hASC during osteoblast differentiation. | ||
| M11494 | Recombinant Human BMP-2 (E.coli) | Recombinant Proteins |
| Bone Morphogenetic Protein 2; BMP-2 | ||
| Recombinant Human BMP-2 was prepared by escherichia coli expression system. Human Bone Morphogenetic Protein-2 (BMP-2) is a bone-growth regulatory factor and belongs to the transforming growth factor-beta (TGF-beta) superfamily. Measured by its ability to induce alkaline phosphatase production by C2C12 cells, the ED50 is typically 0.2-1 µg/ml. | ||
| M14488 | DIPQUO | Phosphatase |
| DIPQUO is an activator of the bone marker alkaline phosphatase (ALP), with an EC50 of 6.27 μM in C2C12 cells. DIPQUO promotes mouse and human osteoblast differentiation via activation of p38 MAPK-β. | ||
| M14496 | SBI-425 | Phosphatase |
| SBI-425 is a potent, selective and oral bioavailable tissue-nonspecific alkaline phosphatase (TNAP) inhibitor. | ||
| M19146 | Trimyristin | AChR/AChE |
| Trimyristin significantly inhibits acetylcholinesterase (AChE), acid and alkaline phosphatase (ACP/ALP) activities in the nervous tissue of Lymnaea acuminata. IC50s of Trimyristin against AChE, ACP, and ALP are 0.11, 0.16 and 0.18 mM, respectively. | ||
| M19381 | Guaiacin | Phosphatase |
| Guaiacin is a arylnaphthalene type lignin isolated from the barks of Machilus thunbergii SIEB. et ZUCC (Lauraceae). Guaiacin significantly increases alkaline phosphatase activity and osteoblast differentiation. | ||
| M20490 | 1-Naphthyl phosphate potassium salt | Phosphatase |
| α-Naphthyl acid phosphate monopotassium salt | ||
| 1-Naphthyl phosphate potassium salt is a non-specific phosphatase inhibitor which acts on acid, alkaline, and protein phosphatases. | ||
| M20854 | L-Homoarginine hydrochloride | Phosphatase |
| L-Homoarginine is a specific inhibitor of liver-type alkaline phosphatase. | ||
| M21663 | Recombinant Mouse DKK-1 (CHO) | Recombinant Proteins |
| Dickkopf-1 | ||
| Dickkopf related protein 1 (DKK-1) is a chemokine that belongs to the DKK protein family, promotes LRP6 internalization and degradation as it forms a ternary complex with the cell surface receptor Kremen. DKK-1 was originally identified as a Xenopus head forming molecule that behaves as an antagonist for Wnt signaling. ED50 < 6.0 µg/ml, measured in stimulation of alkaline phosphatase activity using CCl-226 cells. | ||
| M29194 | Fosmanogepix | Antifungal |
| APX001; E1211 | ||
| Fosmanogepix (APX001) is a first-in-class and orally available broad-spectrum antifungal agent, which targets the highly conserved Gwt1 fungal enzyme. Fosmanogepix (APX001) is an N-phosphonooxymethyl precursor which is rapidly and completely metabolized by systemic alkaline phosphatases to the active moiety, APX001A. Fosmanogepix (APX001) can be used in development for the treatment of invasive fungal infections. | ||
| M39164 | (3R)-7-hydroxy-3-(4-hydroxybenzyl)chromane | Phosphatase |
| (3R)-7-hydroxy-3-(4-hydroxybenzyl)chromane increases the level of alkaline phosphatase (ALP) activity. (3R)-7-hydroxy-3-(4-hydroxybenzyl)chromane promotes mesenchymal stem cells (MSCs) osteogenesis, but cannot enhance MSCs proliferation. | ||
| M39168 | Limocitrin | Phosphatase |
| Limocitrin is a natural product that can be isolated from the buds of P. acerifolia and P. orientalis. Limocitrin suppresses estradiol-dependent proliferation of MCF7 cells weakly but estradiol-induced AlkP (alkaline phosphatase) expression only marginally. | ||
| M43811 | IIAEK | Phospholipase |
| lactostatin | ||
| IIAEK is a novel cholesterol-lowering pentapeptide derived from bovine milk β-lactoglobulin that targets intestinal alkaline phosphatase (IAP) and improves cholesterol metabolism through the specific activation of IAP and down-regulation of ABCA1. Sequence: Ile-Ile-Ala-Glu-Lys | ||
| M43812 | SYN-020 | Phospholipase |
| SYN-020 is an orally active recombinant bovine intestinal alkaline phosphatase (IAP) for studies related to digestive disorders. | ||
| M43825 | APS-5 | Fluorescent Dye |
| Lumigen APS-5 | ||
| APS-5 is a substrate of alkaline phosphatase (ALP). APS-5 can be used to assess the activity of alkaline phosphatase (ALP). | ||
| M50967 | pTH (2-34) (human) | Others |
| pTH (2-34) (human) (80 μg/kg) slightly increases serum osteocalcin levels and alkaline phosphatase activity of bone extract (markers of bone formation) in mice. | ||
| M51244 | Cysteamine S-phosphate sodium | Others |
| Cysteamine S-phosphate (Cystaphos) sodium can be hydroIyzed to Cysteamine by human alkaline phosphatases. | ||
| M54607 | BCIP | Fluorescent Dye |
| BCIP p-toluidine salt; X-phosphate p-toluidine salt | ||
| BCIP is a chromogenic substrate for colorimetric assay of alkaline phosphatase activity. | ||
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